Levicept: Modulating NGF
Levicept hopes NGF modulator may be disease modifying in osteoarthritis
Levicept Ltd.'s p75NTR-Fc could provide the analgesic effect of nerve growth factor inhibitors to treat pain in osteoarthritis without the side effects that have sidelined the class in recent years. This potential made Levicept the first company to graduate from Index Ventures' seed-stage incubator, the Index Nursery, and the company is now raising a series A round.
Pfizer Inc. initially developed p75NTR-Fc; however, the pharma shelved the program when it shuttered its Sandwich, U.K., R&D facility