Arcarios: Protecting chondrocytes
Arcarios developing drugs to prevent progression of bone, joint diseases
Current treatments for osteoarthritis treat the symptoms and relieve pain, but do not target the cause of the disease. Arcarios B.V. has established a preclinical pipeline of compounds to slow or prevent progression of bone and joint diseases by using its screening platforms to identify small molecules and biologics that protect cartilage and bone cells.
Osteoarthritis involves the destruction of cartilage in joints, causing pain, impaired function and destruction of the attached subchondral bone.
Healthy chondrocytes produce and maintain components of the cartilage. But in osteoarthritis, intracellular levels