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Syndexa: De-stressing diabetes

Most marketed diabetes drugs, such as the insulin-sensitizing thiazolidinediones, address the disease's symptoms but have no meaningful impact on progression. Syndexa Pharmaceuticals Corp. thinks its small molecule programs targeting c-jun N-terminal kinase and endoplasmic reticulum stress will address the underlying cause of metabolic diseases. The company hopes to have a candidate from one of the two programs in human testing to treat Type II

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