Proliferating polyclonals

The promise of polyclonal antibodies - collections of antibodies raised against multiple antigens on a target and multiple epitopes on an antigen - has remained elusive because humanized versions have been unavailable. Polyclonals produced by animals induce immune reactions in any human with a functioning immune system, severely limiting their therapeutic applicability.

Therapeutic Human Polyclonals Inc. has developed a way to produce humanized polyclonals in rabbits that SangStat Corp., its new partner, believes will allow polyclonals to be applied in all disease areas where monoclonals have proven effective...