Evotec: Smaller, faster, brighter screening

Confocal microscopy enables the detection of faint and/or small fluorescent signals by eliminating fluorescent light that is outside the plane of focus. Evotec BioSystems GmbH is incorporating a version of confocal microscopy called fluorescence correlation spectroscopy (FCS) into an automated ultra-high throughput screening system that uses submicroliter volumes of reagents, and whose custom software allows drug developers to use the signals to detect meaningful changes in molecular properties.

Evotec's FCS-based screening platform, called EVOscreen, grew out of

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