BioCentury
ARTICLE | Distillery Techniques

Techniques: Mouse model of Crohn's disease with intestinal epithelium barrier disruption

November 5, 2015 8:00 AM UTC

A mouse model of Crohn's disease could be used to screen for therapies to treat the disease. In mice, knockout of P glycoprotein 3 (ABCB1A; MDR/TAP) and infection with Helicobacter bilis recapitulated...