ARTICLE | Distillery Therapeutics
Therapeutics: Kynurenine 3-monoxygenase (KMO)
February 5, 2015 8:00 AM UTC
In vitro and rat studies suggest novel KMO inhibitors could help treat HD. Patients with HD have elevated brain levels of quinolinic acid (QA) and 3-hydroxykynurenine (3-HK) - neurotoxic metabolites t...