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ARTICLE | Distillery Therapeutics

Therapeutics: NLR family pyrin domain containing 3 (NLRP3; NALP3; CIAS1)

April 9, 2015 7:00 AM UTC

In vitro and mouse studies suggest enhancing levels of β-hydroxybutyrate could help treat CAPS and other NLRP3 inflammasome-driven diseases. In an assay of NLRP3 activity in mouse and human macrophage...