ARTICLE | Targets & Mechanisms

Insights into ependymoma

March 27, 2014 7:00 AM UTC

Two independent studies have illuminated the fine molecular details of ependymoma tumors and identified targets for a previously intractable disease. A St. Jude Children's Research Hospital team focused on forebrain ependymomas and identified a fusion protein as a potential target,1 whereas researchers at The Hospital for Sick Children and the German Cancer Research Center focused on hindbrain ependymomas and uncovered epigenetic modifiers.2

In both cases, companies think follow-up studies will be necessary to determine the therapeutic potential of the targets...