ARTICLE | Targets & Mechanisms

Diabetes: A fish story

September 23, 2010 7:00 AM UTC

Researchers at the University of California, San Diego have uncovered a mechanism that could contribute to the therapeutic effects of

GlaxoSmithKline plc's Lovaza, a blockbuster fish oil extract of w-3 fatty acids. It is marketed as an adjunct for dieting to decrease serum triglyceride levels in patients with hypertriglyceridemia, a condition with multiple causes including diabetes. The team found that w-3 fatty acids exert their anti-inflammatory and insulin-sensitizing effects through G protein-coupled receptor 120.1...