ARTICLE | Tools & Techniques

Cell-free joint regeneration

August 19, 2010 7:00 AM UTC

Columbia University Medical Center researchers have identified a cell-free tissue-regeneration strategy that not only helps replace lost bone but also regenerates cartilage, a feat that has stymied previous joint replacement efforts.1

Treatments for the structural breakdown of bone and cartilage that occurs in osteoarthritis include total joint replacement with a metallic or synthetic prosthetic. The devices do a good job of mimicking joint function, but wear between the patient's bone and the device can lead to loosening of the prosthetic, infection and failure after 10-15 years.2...