To include your compound in the COVID-19 Resource Center, submit it here.

Models for QT prolongation

A group at the Technion Israel Institute of Technology and a team at the Stanford University School of Medicinehave independently developed human stem cell-based models of long QT syndrome,1,2 a potentially fatal cardiac disorder that can be triggered by environmental and pharmacological stimuli in susceptible patients. The models could be used to identify potential therapies for long QT syndrome as well as compounds that induce QT prolongation as a side effect-a problem that has derailed many drug development programs.

Of the 12 subtypes of long QT syndrome, the two most common-LQT1 and

Read the full 914 word article

Trial Subscription

Get a two-week free trial subscription to BioCentury


Article Purchase

This article may not be distributed to non-subscribers