ARTICLE | Translation in Brief

The Thetis thesis

Thetis' TP-113 improves on metformin

September 3, 2015 7:00 AM UTC

Thetis Pharmaceuticals LLC believes it can improve upon the diabetes drug metformin with TP-113, a small molecule that delivers both metformin and docosahexaenoic acid (DHA) orally, and can reduce insulin resistance while treating diabetes.

Metformin is an established first-line therapy for Type II diabetes that reduces glucose levels, and DHA is an omega fatty acid found in fish oils that's been associated with cardiovascular effects because it can reduce triglyceride levels. ...