Therapeutics: Cyclin dependent kinase 1 (CDK1; CDC2); CDK2; centrosomal protein 290kDa (CEP290)

In vitro and mouse studies suggest inhibiting CDK1 and CDK2 could help treat Joubert syndrome cases caused by loss-of-function mutations in CEP290. Levels of CDK1 and CDK2 were higher in primary kidne...