BioCentury
ARTICLE | Clinical News

Presidio preclinical data

May 7, 2012 7:00 AM UTC

In 3-day HCV genotype 1a, 1b, 2a, 3a and 4a replicon assays, oral PPI-383 inhibited all HCV genotypes with EC50 values ranging from 2.2-11.7 nM. In rats, monkeys and dogs, the non-nucleoside HCV NS5B...