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Cabozantinib: Interim Phase II data

Updated interim data from 490 evaluable patients with various solid tumors in the lead-in stage of an ongoing, adaptive, international Phase II trial showed that once-daily oral cabozantinib led to 12-week overall disease control rates (DCRs) of 73%, 68%, 53%, 47%, 45% and 40% for patients with hepatocellular carcinoma (HCC), castration-resistant prostate cancer (CRPC), ovarian cancer, melanoma, breast cancer and non-small cell lung cancer (NSCLC), respectively. Lower 12-week DCRs were observed in patients with small cell lung cancer

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