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Gilead other research news

November 4, 1996 8:00 AM UTC

GILD and colleagues at the Sunnybrook Health Science Center in Toronto showed that p27, a cyclin-dependent kinase inhibitor known to be up-regulated by intercellular contact in normal cells, plays a role in the resistance of certain slow-growing tumors to chemotherapeutics.

The multiple drug resistance (MDR) gene is responsible for some, but not all, of the resistance of tumors to chemotherapy. GILD and colleagues have now shown in Nature Medicine that p27 is also responsible. ...