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ARTICLE | Company News

R.W. Johnson Pharmaceutical Research Institute other research news

April 1, 1996 8:00 AM UTC

Researchers reported in Nature that they were able to block a factor Xa receptor on lymphocytes, called effector cell protease receptor-1 (EPR-1), with the 2E1 monoclonal antibody or an antisense oligonucleotide. Such blocking in SCID mice inhibited CD3/T cell receptor-dependent lymphocyte proliferation, which is required to produce an immune response. ...