BioCentury
ARTICLE | Clinical News

CD4 analog data

April 25, 1994 7:00 AM UTC

Researchers used a rationally designed, small synthetic analog of the CD4 protein surface to inhibit the incidence and severity of an animal model of multiple sclerosis.

They noted in Nature that using the analog could avoid the inherent immunogenicity of the anti-CD4 monoclonal antibodies now in clinical trials, and moreover would spare the CD4 subset of T cells. ...