BioCentury
ARTICLE | Clinical News

AmBisome liposomal amphotericin B data

September 23, 1996 7:00 AM UTC

Phase III data that will be included in NXTR’s NDA were presented at the Interscience Conference on Antimicrobial Agents and Chemotherapy, showing earlier sterilization of the cerebrospinal fluid with the liposomal AmBisome compared to treatment with free amphotericin B.

The trial showed a lower rate of kidney toxicity with AmBisome, with mean time to sterilization of 14 days, compared to more than 21 days with the free antifungal. ...