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National Institute of Arthritis and Musculoskeletal and Skin Diseases other research news

September 3, 1996 7:00 AM UTC

NIAMS researchers published research in Nature Genetics detailing the localization of six distinct genetic regions that control arthritis in a rat model. In rats with collagen-induced arthritis, as in humans, major histocompatibility complex (MHC) genes are known to be involved in determining the susceptibility to arthritis in some, but not all, individuals. The scientists have now shown that non-MHC genes affect arthritis susceptibility and severity in rats. ...