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MRC Laboratory of Molecular Biology other research news

October 14, 1996 7:00 AM UTC

British researchers reported that the tau protein, involved in the brain damage seen in Alzheimer's, can be altered by heparin. As published in Nature, heparin and other sulphated glycosaminoglycans induce tau to adopt the form that aggregates into the neurofibrillary tangles that are a hallmark of the disease. Heparin and tau are found together in nerve cells of Alzheimer's brains at the earliest stages of the neurofibrillary pathology. ...