University of Ulm other research news

University researchers reported in Nature their work on a mouse model of psoriasis. They transplanted 18 full thickness skin grafts from clinically uninvolved areas of 3 psoriatic patients onto SCID mice lacking B and T cells. Grafts injected with 3 µg of the bacterial superantigen exfoliative toxin showed some of the hallmarks of psoriasis, they reported. These included profound epidermal thickening from hyperproliferating basal keratinocytes, and increased indentation of epidermis and dermis. ...