Agouron preclinical data

AG2034 inhibited growth of a broad range of murine and human tumor xenografts in preclinical studies when given daily or twice weekly. GART (glycinamide ribonucleotide formyl transferase) is key to the biosynthesis of purine nucleotides, which are necessary for the proliferation of tumor cells. The results were presented at the American Association for Cancer Research meeting in Washington. ...