Agouron preclinical data

AG3340, given in daily doses of 50 mg/kg, completely halted growth of Lewis lung carcinomas in two-thirds of mice tested, and reduced the formation of lung metastases (>5 mm) by 90 percent. AG3340 was active either orally or intraperitoneally, and was well-tolerated. The data were presented at the American Association for Cancer Research meeting in Washington. ...