University of Cologne, Germany, et. al. other research news

University researchers in Europe published an improved method of knocking out genes in mice.

As reported in Science, the method uses the inducible promoter of the Mx1 gene to control the expression of a Cre recombinase transgene. Mx1, part of the defense to viral infections, is silent in healthy mice. The gene then is flanked by recombinase recognition (loxP) sites. ...