Gladstone Institute of Cardiovascular Disease other research news

Research at the Gladstone Institute, which is affiliated with the University of California at San Francisco, has uncovered unintended consequences of a gene therapy method that was designed to lower low density lipoprotein (LDL) levels in blood.

As published in the Proceedings of the National Academy of Sciences, an attempt to engineer into transgenic animals a gene that edits messenger RNA, to lower LDL levels, resulted in malignancy in the animals. ...