BioCentury
ARTICLE | Clinical News

Emisphere preclinical data

October 30, 1995 8:00 AM UTC

EMIS (Hawthorne, N.Y.) published chemical characteristics of its microsphere compounds that enhance delivery of peptides through the gastrointestinal tract, and showed in animal experiments that salmon calcitonin, alpha-interferon, and heparin can be given orally using these agents.

As reported in the Journal of Medicinal Chemistry, therapeutic levels of the drugs were achieved in rats and monkeys. ...