Walter Reed Army Institute of Research other research news

Army researchers published findings with weakened Shigella bacteria showing the ability to direct cells to make functional foreign protein.

As reported in Science, the vector was created as a deletion mutation in the asd gene that codes for an essential enzyme for a constituent of the bacteria's cell wall. The construct strain was able to express, in mammalian cells, the eukaryotic vector pCMVbeta, and E. coli galactosidase under control of a cytomegalovirus promoter. ...