BioCentury
ARTICLE | Clinical News

Heparinase I data

May 2, 1994 7:00 AM UTC

Montreal-based Ibex, a subsidiary of Continental Pharma Cryosan Inc., presented preclinical results on the ability of heparinase I to reverse the effects of the anticoagulant heparin.

Dog studies were presented at the Cardiovascular Anesthesiologist meeting in Montreal comparing the hemodynamic effects of heparinase I to protamine, the drug commonly used to reverse heparin. Protamine has a number of side effects, including decreased systemic blood pressure, increased pulmonary blood pressure and decreased cardiac index. ...