ARTICLE | Clinical News

Xenova preclinical data

December 12, 1994 8:00 AM UTC

Studies in a rat carotid artery model of thrombosis showed the natural inhibitor and synthetic derivatives to be at least as effective as aspirin and heparin in controlling blood clots, without the undesirable effects on bleeding time or platelet aggregation.

The agents increased the time to vessel occlusion (p<0.01, 19 experiments, for the natural inhibitor; p<0.01 and 0.05 for the synthetic derivatives). ...