GLQ223 alpha-trichosanthin data

GNLB presented preliminary results of a Phase II study in 148 patients with AIDS and AIDS-related complex showing a trend towards more treatment failures in patients treated with AZT as compared with GLQ223 (p= 0.09).

Patients received GLQ223, AZT, or both drugs. Entry criteria included being treated with AZT for at least nine moths and CD4 counts of 200-500. Side effects included flu-like symptoms, allergic reactions and elevations in muscle and liver enzymes, all of which were clinically manageable, GNLB said. ...