BioCentury
ARTICLE | Clinical News

Tissue engineered cartilage substitute data

October 18, 1993 7:00 AM UTC

ATIS presented results with its engineered cartilage as replacement tissue for the human nose. The company reported animal data showing that an implant of a biodegradable mesh seeded with cartilage cells can be grown in culture for a week to create an implant that retained shape and was not rejected by the recipients. Inflammation was not seen during the eight weeks of the experiment, which was reported at the Clinical Congress of the American College of Surgeons in San Francisco. Natural cartilage doesn't spontaneously heal or regenerate after injury.

The mesh is made of polyglycolic acid. Over time, this matrix disappears and new cartilage grows as the implant is accepted by the body. ...