BioCentury
ARTICLE | Clinical News

Oxygent perflubron: Phase III

December 18, 2000 8:00 AM UTC

ALLP said further analysis of its 492-patient Phase III trial showed that Oxygent significantly reduced the number of units of donor blood needed during general surgery (p=0.013), the trial's primary end point, and reduced the usage of blood transfusions overall (p=0.038) (see BioCentury, Sept. 18). Among 424 patients who experienced at least 10 mL/kg blood loss (up to >80 mL/kg in some cases), Oxygent also significantly reduced the number of transfused units (p<0.001) and usage of blood transfusions (p=0.002) through day 21 post-surgery. Data were presented at the Postgraduate Assembly in Anesthesiology meeting in New York. ...