Lisofylline data

The Seattle company presented animal data at the International Conference on Tumor Necrosis Factor and Related Cytokines in Monterey, Calif., demonstrating the ability of Lisofylline to increase survival in models of endotoxin-induced lethality, and in lung injury after hemorrhagic shock.

The methylxanthine inhibitor of phosphatidic acid (PA) formation significantly inhibited lung damage in mice who lost 30 percent of their blood (p < 0.05 on two measures). ...