Chiron other research news

The Emeryville, Calif., company demonstrated that its method of synthesizing peptoid (peptide-like) small molecules can generate drug candidates.

In the Journal of Medicinal Chemistry, company researchers targeted two members of the family of receptors that activate G proteins, and which thereby direct intracellular traffic. The library generated by automated peptoid synthesis yielded several chemically new, high-affinity ligands for an adrenergic and an opioid receptor. CHIR plans to continue testing the agents as possible therapeutics. ...