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12:35 PM, Oct 19, 2018  |  BC Week In Review | Company News  |  Deals

Sarepta gets gene therapy candidate, Lysogene extends runway

Lysogene S.A. (Euronext:LYS) granted Sarepta Therapeutics Inc. (NASDAQ:SRPT) exclusive, ex-European rights to LYS-SAF302, an adeno-associated virus (AAV)-mediated gene therapy. Sarepta will pay $15 million up front and make a $2.5 million equity investment in Lysogene,...
12:14 PM, Oct 19, 2018  |  BC Week In Review | Company News  |  Deals

HiFiBiO Therapeutics acquires H-Immune

HiFiBiO Therapeutics (Cambridge, Mass.) acquired H-Immune Therapeutics S.A.S. (Paris, France) for an undisclosed sum. H-Immune is developing a pipeline of immuno-oncology focused human antibodies generated using the company's in vitro immunization platform. The biotech spun...
11:37 AM, Oct 19, 2018  |  BC Week In Review | Company News  |  Deals

AbbVie, Morphic partner on antifibrotic integrins

AbbVie Inc. (NYSE:ABBV) agreed to pay Morphic Therapeutic (Waltham, Mass.) $100 million up front for exclusive options to license antifibrotic integrins to block transforming growth factor β (TGFβ) activation via multiple undisclosed targets. Morphic is responsible...
11:33 AM, Oct 19, 2018  |  BC Week In Review | Company News  |  Deals

SQZ, Roche expand deal to jointly develop cancer cell therapies

SQZ Biotechnologies Co. (Watertown, Mass.) and Roche (SIX:ROG; OTCQX:RHHBY) expanded a 2015 deal to co-develop and commercialize antigen presenting cell (APC) therapies to treat cancers that are difficult to address with other adoptive cell therapy...
11:08 AM, Oct 19, 2018  |  BC Week In Review | Company News  |  Deals

Novartis buys Endocyte for $2.1B, gets radioligand therapy for prostate cancer

Novartis AG (NYSE:NVS; SIX:NOVN) will acquire cancer company Endocyte Inc. (NASDAQ:ECYT) for about $2.1 billion in cash. The deal gives Novartis 177Lu-PSMA-617, a radioligand therapy in the Phase III VISION trial to treat prostate-specific membrane...
11:06 AM, Oct 19, 2018  |  BC Week In Review | Company News  |  Deals

Xyphos, Parker Institute steer next-gen Car T therapies into solid tumors

Xyphos Biosciences Inc. (South San Francisco, Calif.) will partner with the Parker Institute for Cancer Immunotherapy to develop CAR Ts using Xyphos' convertibleCAR platform. Xyphos President and CEO Jim Knighton told BioCentury the research will...
10:59 AM, Oct 19, 2018  |  BC Week In Review | Company News  |  Deals

J&J stalls development of antiviral from Alios deal

Johnson & Johnson (NYSE:JNJ) has stalled development of lumicitabine (AL-8176), an antiviral candidate that was a key to its $1.75 billion acquisition of Alios BioPharma Inc. in 2014, and revealed a resulting impairment charge of...
10:40 AM, Oct 19, 2018  |  BC Week In Review | Company News  |  Deals

Revolution acquiring Warp Drive

Revolution Medicines Inc. (Redwood City, Calif.) is expanding its cancer pipeline with the acquisition of another Third Rock Ventures portfolio company, Warp Drive Bio Inc. (Cambridge, Mass.). The financial terms of the deal are undisclosed...
10:34 AM, Oct 19, 2018  |  BC Week In Review | Company News  |  Deals

GEn1E gains option to p38 MAPK inhibitor

GEn1E Lifesciences Inc. (Palo Alto, Calif.) gained an exclusive option to license a patent application from the University of Maryland Baltimore (Baltimore, Md.) covering methods and use of p38 mitogen-activated protein kinase (p38 MAPK; MAPK14)...
10:32 AM, Oct 19, 2018  |  BC Week In Review | Company News  |  Deals

Gurnet to acquire Corium as it heads for NDA

Healthcare investor Gurnet Point Capital will acquire drug delivery company Corium International Inc. (NASDAQ:CORI) for $12.50 per share in cash plus $0.50 per share in a contingent value right (CVR). The deal, including the CVR,...

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