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3 items
12:00 AM, Mar 20, 2008  |  BC Innovations | Markers

Micro Management

In the past four years, at least two biotechs have released tests that use mRNA-based gene signatures to predict the likelihood of breast cancer recurrence. Now, research is emerging that suggests microRNAs could also have...
12:00 AM, Mar 06, 2008  |  BC Innovations | Markers

mTOR Caveats

In many tumor types, rapamycin is thought to inhibit mammalian target of rapamycin's regulation of a key transcription factor-hypoxia-inducible factor-1a-that is involved in tumor cell growth and proliferation. A widely used biomarker therefore relies on...
12:00 AM, Jan 31, 2008  |  BC Innovations | Markers

Locus swarm

Although whole-genome association studies in the autoimmune space are increasingly common, their predictive value is still limited. The main reason is that autoimmune diseases have multiple genetic causes, and any one risk factor will only...