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12:00 AM, Jun 03, 2013  |  BioCentury | Strategy

Taiho goes global

oral combination of tegafur and uracil, a pyrimidine that improves the drug's half-life by inhibiting dihydropyrimidine dehydrogenase
for solid tumors. TAS-114 is a first-in-class dual inhibitor of deoxyuridine 5'-triphosphate nucleotidehydrolase (dUTPase) and dihydropyrimidine dehydrogenase
12:00 AM, Jul 07, 2008  |  BioCentury | Strategy

Flurizan’s failure adds value

assesses risk of toxicity due to 5-FU/capecitabine-based chemotherapy by detecting variations in the genes encoding dihydropyrimidine dehydrogenase