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8 results
3:00 PM, Mar 22, 2018  |  BC Innovations | Strategy

Janssen’s virtual discovery

useful for difficult-to-drug targets, where identifying diverse scaffolds can be key. He cited GPR81, a GPCR
will remember this paper in the future.” Martin Brenner, Recursion By contrast, traditional kinase and GPCR
3:13 PM, Jan 25, 2018  |  BC Innovations | Strategy

Takeda rides Denali’s ATV

per product Oct. 2012 Heptares Therapeutics Ltd. (C) Products against undisclosed G protein coupled receptor (GPCR
III in Europe ¥10B ($120M) $180M March 2011 Evotec AG (Xetra:EVT) Small molecule modulators against GPCR
8:45 PM, Apr 06, 2017  |  BC Innovations | Strategy

Pushing for progress in Prader-Willi

snoRNA) Gene loss causes growth deficiency, anxiety and hyperphagia Serotonin (5-HT2C) receptor G protein-coupled receptor (GPCR
12:00 AM, Dec 04, 2014  |  BC Innovations | Strategy

Incubating innovation

final project is really a drug discovery-enabling technology to facilitate the discovery and optimization of GPCR
12:00 AM, Sep 04, 2014  |  BC Innovations | Strategy

Funding forgotten proteins

A new NIH program is highlighting understudied members of druggable protein classes including GPCRs, kinases, nuclear …
NIH has allocated $5.8 million to fund 7 research projects that explore the biology of GPCRs …
to identify functions of the druggable genome Automated live-cell imaging with fluorescent biosensors to study GPCR
12:00 AM, Jun 12, 2014  |  BC Innovations | Strategy

CQDM: Canada on the brain

Completed Focus projects include biosensors that predict the efficacy and side effects of drugs targeting GPCRs …
version. In another partnership, Pfizer Inc. and the University of Montreal researcher who led the GPCR
12:00 AM, Dec 05, 2013  |  BC Innovations | Strategy

A conversation with Chris Lipinski

log P greater than 3 and a molecular weight greater than 400 you'll discover many GPCR
about every possible protein-protein interaction target and you'll have a lot of trouble with peptidergic GPCRs …
12:00 AM, Mar 14, 2013  |  BC Innovations | Strategy

GSK goes deep with DPAc

to identify positive allosteric modulators of melanocortin 4 receptor ( MC4R ). MC4R is a GPCR