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5 results
1:55 PM, Jul 27, 2017  |  BC Innovations | Translation in Brief

Sepsis' sweet tooth

mouse models increased survival at day 14 from 25% to 60%. Adenoviral vector-mediated overexpression of ferritin heavy polypeptide 1 (FTH1
2:04 PM, Jul 18, 2017  |  BC Innovations | Distillery Therapeutics

Infectious disease

INDICATION: Sepsis Mouse studies suggest ferritin or promoting FTH1 expression could help treat sepsis. In a …
mouse model of cecal ligation and puncture (CLP)-induced sepsis, adenoviral-mediated overexpression of FTH1 in the liver …
the effect of heme on iron-regulated glucose production in malaria and other infections. TARGET/MARKER/PATHWAY: Ferritin; ferritin heavy polypeptide 1 (FTH1
12:00 AM, Aug 27, 2015  |  BC Innovations | Distillery Therapeutics

Therapeutics: Ferritin heavy polypeptide 1 (FTH1); interleukin-1 (IL-1) β

Neurology INDICATION: Neurology Studies in cells and rats suggest inhibiting FTH1 or IL-1β could help treat …
HIV-associated neurocognitive disorders. FTH1 levels were higher and dendritic spine density was lower in the brains …
disorder than in normal rat brains. In cortical neurons from the rat models, shRNA targeting FTH1
12:00 AM, Mar 05, 2009  |  BC Innovations | Distillery Therapeutics

Indication: Neurology

information Neurology Nerve damage Chemokine (CXC motif) receptor 4 (CXCR4; NPY3R); ferritin, heavy polypeptide 1 (FTH1
12:00 AM, Jan 29, 2009  |  BC Innovations | Distillery Therapeutics

Indication: Various

Summary Licensing status Publication and contact information Various Cancer; diabetic retinopathy Ferritin, heavy polypeptide 1 (FTH1