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12:00 AM, Mar 24, 2016  |  BC Innovations | Distillery Therapeutics

Therapeutics: MicroRNA-219 (miR-219)

Neurology INDICATION: Schizophrenia Patient sample and cell culture studies suggest inhibiting miR-219 could help treat schizophrenia …
which has been associated with low neural stem cell proliferation. Levels of miR-219 were higher in …
normal human neural stem cells. In patient-derived neural stem cells, viral-mediated delivery of an oligonucleotide miR-219
12:00 AM, Dec 05, 2013  |  BC Innovations | Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Bone metastases MicroRNA-141 (miR-141); miR-219 Cell …
culture and mouse studies suggest miR-141 and miR-219 could help prevent bone metastases. In cultured pre-osteoclasts …
medium from weakly metastatic tumors did not. miRNA profiling identified 5 miRNAs, including miR-141 and miR-219