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12:00 AM, Feb 11, 2013  |  BioCentury | Emerging Company Profile

GeneCentric: Cancer sign-off

to an anti-angiogenesis drug, she said. The gene signature, also licensed from UNC, includes VEGF, angiopoietin-like 4
ANGPTL4) , adrenomedullin (ADM; AM) and solute carrier family 16 member 3 (SLC16A3) . Perou was …
12:00 AM, Dec 03, 2012  |  BioCentury | Emerging Company Profile

Lipigon: LPL protectorate

activity to about 60,000 ester bonds per minute. By contrast, in disease states, inhibitors including angiopoietin-like 4
ANGPTL4) and apolipoprotein C-III ( APOCIII ; APOC3 ) become overly active and cleave LPL into …
12:00 AM, Jul 09, 2007  |  BioCentury | Tools & Techniques

Lexicon's lipid-lowering antibody

intends to develop a lipid-regulating antibody for use in severe cardiovascular disease. Angiopoietin-like protein 4 (Angptl4
Proceedings of the National Academy of Sciences, LXRX (The Woodlands, Texas) showed that antibodies against Angptl4
and high-fat diets injected intraperitoneally once per week with 30 mg/kg of the company's 14D12 anti-Angptl4