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11:09 AM, Jan 18, 2017  |  BC Innovations | Distillery Therapeutics

Neurology

layer, compared with normal NAT8L expression. Next steps include identifying and testing NAT8L inhibitors. TARGET/MARKER/PATHWAY: N-acetyltransferase 8
12:00 AM, Feb 09, 2012  |  BC Innovations | Distillery Therapeutics

Indication: Neurology

Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Alzheimer's disease (AD) N-Acetyltransferase 8 (NAT8); NAT8B Human …
brain tissue and cell culture studies suggest NAT8 and NAT8B could be antagonized to treat AD …
In brain tissue from AD patients, compared with healthy control tissue, NAT8 and NAT8B were overexpressed …
12:00 AM, Apr 29, 2010  |  BC Innovations | Distillery Therapeutics

Indication: Renal disease

Indication Target/marker/ pathway Summary Licensing status Publication and contact information Renal disease Renal disease N-acetyltransferase 8 GCN5-related …
putative (NAT8); solute carrier family 7 cationic amino acid transporter y+ system member 9 (SLC7A9) A …
kidney disease (CKD). Genetic analysis of CKD patients of European descent showed that rs10206899 near NAT8