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9:13 AM, Aug 16, 2018  |  BC Innovations | Distillery Therapeutics

Cancer

INDICATION: Breast cancer In vitro and cell culture studies identified a dual CDK12/CDK13 inhibitor that could …
assays followed by structure-based optimization of hits yielded an arylurea analog that inhibited CDK12 and CDK13
Pharmaceutical Co. Ltd. include further optimization of the compound. TARGET/MARKER/PATHWAY: Cyclin dependent kinase 12 (CDK12); CDK13
12:00 AM, Apr 14, 2016  |  BC Innovations | Product R&D

AACR by the numbers

help treat or prevent bone metastasis of NSCLC. Van Andel Institute 1565 Cyclin-dependent kinase 13 (CDK13
Sarcoma Studies in cancer cell lines suggest inhibiting CDK12 and CDK13 could help treat Ewing sarcoma …