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Valchlor, mechlorethamine (mechlorethamine gel)

Also known as: Clearazide, chlormethine

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Collapse Summary General Information
Company Actelion Ltd.
DescriptionTopical form of nitrogen mustard, an alkylating agent
Molecular Target DNA
Mechanism of ActionDNA damage removal
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationCutaneous T cell lymphoma (CTCL)
Indication DetailsTreat cutaneous T cell lymphoma (CTCL); Treat early-stage mycosis fungoides-type cutaneous T cell lymphoma (CTCL)
Regulatory Designation

U.S. - Fast Track (Treat early-stage mycosis fungoides-type cutaneous T cell lymphoma (CTCL));
U.S. - Orphan Drug (Treat early-stage mycosis fungoides-type cutaneous T cell lymphoma (CTCL));
U.S. - Special Protocol Assessment (Treat cutaneous T cell lymphoma (CTCL));
U.S. - Undisclosed Review (Treat early-stage mycosis fungoides-type cutaneous T cell lymphoma (CTCL));
EU - Orphan Drug (Treat cutaneous T cell lymphoma (CTCL))

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