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Topical XEN402, TV-45070

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Company Xenon Pharmaceuticals Inc.
DescriptionTopical formulation of sodium channel sub-type Nav1.7 (SCN9A) blocker
Molecular Target Nav1.7 (SCN9A)
Mechanism of ActionNa channel blocker
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPhase II
Standard IndicationPain
Indication DetailsTreat osteoarthitis (OA) pain; Treat pain associated with erythromelalgia; Treat postherpetic neuralgia (PHN)
Regulatory Designation

U.S. - Orphan Drug (Treat pain associated with erythromelalgia)


Teva Pharmaceutical Industries Ltd.

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