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Trisenox, arsenic trioxide

Also known as: ATO

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Company Teva Pharmaceutical Industries Ltd.
DescriptionArsenic trioxide that causes DNA fragmentation and damage to promyelocytic leukemia-retinoic acid receptor alpha (PML-RARA) fusion protein
Molecular Target DNA
Mechanism of ActionUnknown
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationAcute promyelocytic leukemia (APL)
Indication DetailsTreat acute promyelocytic leukemia (APL); Treat refractory acute promyelocytic leukemia (APL); Treat relapsed or refractory acute promyelocytic leukemia (APL)
Regulatory Designation

Australia - Orphan Drug (Treat acute promyelocytic leukemia (APL))


H. Lundbeck A/S; Nippon Shinyaku Co. Ltd.

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