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Treximet, sumatriptan/naproxen (formerly Trexima)

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Company Pozen Inc.
DescriptionCombination of sumatriptan and naproxen sodium
Molecular Target Serotonin (5-HT1B) receptor ; Serotonin (5-HT1D) receptor
Mechanism of Action 
Therapeutic ModalitySmall molecule: Combination
Latest Stage of DevelopmentMarketed
Standard IndicationMigraine
Indication DetailsTreat acute migraine; Treat acute migraine, with or without aura, in adults; Treat migraine in adolescents; Treat migraine in patients with a poor response or intolerance to short-acting triptan treatment; Treat probable migraine
Regulatory Designation

U.S. - Priority Review (Treat migraine in adolescents)


GlaxoSmithKline plc; Pernix Therapeutics Holdings Inc.

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