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TGR5, XL475

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Company Exelixis Inc.
DescriptionOral, small molecule agonist of TGR5
Molecular Target G protein-coupled bile acid receptor 1 (GPBAR1) (TGR5)
Mechanism of ActionG protein-coupled bile acid receptor 1 (TGR5) agonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPreclinical
Standard Indication Metabolic (unspecified)
Indication DetailsTreat metabolic disorders
Regulatory Designation
PartnerBristol-Myers Squibb Co.

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